The Journal of antimicrobial chemotherapy
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J. Antimicrob. Chemother. · Apr 2014
Randomized Controlled Trial Multicenter StudyEffect of clarithromycin in patients with suspected Gram-negative sepsis: results of a randomized controlled trial.
A previous randomized study showed that clarithromycin decreases the risk of death due to ventilator-associated pneumonia and shortens the time until infection resolution. The efficacy of clarithromycin was tested in a larger population with sepsis. ⋯ Intravenous clarithromycin did not affect overall mortality; however, administration shortened the time to resolution of infection and decreased the hospitalization costs.