The Journal of antimicrobial chemotherapy
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J. Antimicrob. Chemother. · Apr 2015
Review Meta AnalysisAssociation between oral fluoroquinolone use and the development of retinal detachment: a systematic review and meta-analysis of observational studies.
Several observational studies have been published investigating the association between oral fluoroquinolone use and the development of retinal detachment; however, the findings are not concordant. This study is a meta-analysis of the existing literature and estimates the overall absolute risk of such an event. ⋯ The findings of this systematic review and meta-analysis do not support an association between oral fluoroquinolone use and the development of retinal detachment. Given the low absolute risk, such an event would be rare if there were an association. The current prescribing practice for fluoroquinolones should not be altered because of a previously suggested potential risk of retinal detachment.