The New England journal of medicine
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Randomized Controlled Trial Clinical Trial
Serum antibody responses after intradermal vaccination against influenza.
If found to be safe and immunogenic, reduced doses of influenza vaccine given by the intradermal route could increase the number of available doses of vaccine. ⋯ As compared with an intramuscular injection of full-dose influenza vaccine, an intradermal injection of a reduced dose resulted in similarly vigorous antibody responses among persons 18 to 60 years of age but not among those over the age of 60 years.
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Comparative Study
Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia.
Data regarding the outcome of cord-blood transplantation in adults are scant, despite the fact that these grafts are increasingly used in adults. ⋯ HLA-mismatched cord blood should be considered an acceptable source of hematopoietic stem-cell grafts for adults in the absence of an HLA-matched adult donor.