The New England journal of medicine
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Randomized Controlled Trial Multicenter Study
Effect of human rotavirus vaccine on severe diarrhea in African infants.
Rotavirus is the most common cause of severe gastroenteritis among young children worldwide. Data are needed to assess the efficacy of the rotavirus vaccine in African children. ⋯ Human rotavirus vaccine significantly reduced the incidence of severe rotavirus gastroenteritis among African infants during the first year of life. (ClinicalTrials.gov number, NCT00241644.)