The New England journal of medicine
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Randomized Controlled Trial Multicenter Study
Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.
The use of levothyroxine to treat subclinical hypothyroidism is controversial. We aimed to determine whether levothyroxine provided clinical benefits in older persons with this condition. ⋯ Levothyroxine provided no apparent benefits in older persons with subclinical hypothyroidism. (Funded by European Union FP7 and others; TRUST ClinicalTrials.gov number, NCT01660126 .).