The New England journal of medicine
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Editorial Comment
Scratching the Endometrium in In Vitro Fertilization - Time to Stop.
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Randomized Controlled Trial Multicenter Study Comparative Study
Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria.
Tafenoquine, a single-dose therapy for Plasmodium vivax malaria, has been associated with relapse prevention through the clearance of P. vivax parasitemia and hypnozoites, termed "radical cure." ⋯ Among patients with normal G6PD enzyme activity, the decline in hemoglobin level with tafenoquine did not differ significantly from that with primaquine. Tafenoquine showed efficacy for the radical cure of P. vivax malaria, although tafenoquine was not shown to be noninferior to primaquine. (Funded by GlaxoSmithKline and Medicines for Malaria Venture; GATHER ClinicalTrials.gov number, NCT02216123 .).