Archives of pathology & laboratory medicine
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Arch. Pathol. Lab. Med. · Sep 2014
Multicenter Study Comparative StudyTrends in parenteral direct thrombin inhibitor use in pediatric patients: analysis of a large administrative database.
Parenteral direct thrombin inhibitors (DTIs) may be used in pediatric patients with contraindications to heparin therapy, such as heparin-induced thrombocytopenia. Few data exist regarding the use of DTIs in pediatric patients. ⋯ Pediatric use of DTIs is infrequent and occurs in patients with high morbidity and mortality.