The Journal of hand surgery
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Randomized Controlled Trial
Dexmedetomidine reduces the ischemia-reperfusion injury markers during upper extremity surgery with tourniquet.
We examined the effect of dexmedetomidine on ischemia-reperfusion injury due to tourniquet application during upper-extremity surgery by determining blood malondialdehyde and hypoxanthine levels. Alterations in aspartate aminotransferase, alanine aminotransferase, creatine phosphokinase, lactate dehydrogenase, uric acid, and creatinine levels were also assessed. ⋯ Prognostic II.
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Randomized Controlled Trial Comparative Study
A prospective randomized controlled trial of injection of dexamethasone versus triamcinolone for idiopathic trigger finger.
This study was designed to test the null hypothesis that there is no difference in resolution of triggering 3 months after injection with either a soluble (dexamethasone) or insoluble (triamcinolone) corticosteroid for idiopathic trigger finger. ⋯ Although there were no differences 3 months after injection, our data suggest that triamcinolone may have a more rapid but ultimately less durable effect on idiopathic trigger finger than does dexamethasone.
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Randomized Controlled Trial
A prospective, randomized, controlled trial of 2-octylcyanoacrylate versus suture repair for nail bed injuries.
To prospectively compare the efficacy of 2-octylcyanoacrylate (Dermabond; Ethicon Inc, Somerville, NJ) with standard suture repair in the management of nail bed lacerations. ⋯ Therapeutic I.
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Randomized Controlled Trial Comparative Study
Hylan versus corticosteroid versus placebo for treatment of basal joint arthritis: a prospective, randomized, double-blinded clinical trial.
Conservative, nonsurgical therapies for basal joint osteoarthritis, such as thumb spica splinting and intra-articular corticosteroid injections, remain the mainstays for symptomatic treatment. This study compares intra-articular hylan, corticosteroid, and placebo injections with regard to pain relief, strength, symptom improvement, and metrics of manual function in a randomized, controlled, double-blinded study. ⋯ Therapeutic I.
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Randomized Controlled Trial
Extra-articular steroid injection: early patient response and the incidence of flare reaction.
To evaluate the timing of improvement after extra-articular steroid injection, the incidence of a postinjection pain flare (a delayed postinjection transient increase in pain), and the role of the injection acidity in the postinjection flare. ⋯ Therapeutic I.