Spine
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A biomechanical study was designed to assess implant cut-out of three different angular stable anterior spinal implants. Subsidence of the implant relative to the vertebral body was measured during an in vitro cyclic loading test. ⋯ Implant stability within each implant group was influenced by BMD and load bearing cross-sectional area. The angulation of the two screws did not have a significant influence on cut-out. As conclusion from this study, promising approaches for further implant development are: 1) increase of load-bearing cross-sectional area (e.g., larger outer diameter of the anchorage device), 2) screw positioning in areas of higher BMD (e.g., opposite cortex, proximity to pedicles or the endplates).
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The mechanisms behind the formation of a characteristic tissue reaction at the surface of the dorsal root ganglion (DRG) exposed to nucleus pulposus was studied with special reference to apoptosis using electron microscopy and immunohistochemistry in rats. ⋯ Nucleus pulposus herniated from the disc induced apoptosis in at the surface of the DRG exposed to nucleus pulpous as early as 24 hours after exposure.
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Randomized Controlled Trial Comparative Study
Comparing a supine radiologic versus standing clinical measurement of kyphosis in older women: the Fracture Intervention Trial.
A study of agreement between different measures of kyphosis, a clinical standing measure (Debrunner kyphometer; Protek AG, Bern, Switzerland) versus a supine radiologic measure (Cobb angle). ⋯ There is reasonable agreement between a supine radiologic and standing clinical measurement of kyphosis in older women.
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Comparative Study
Estimating SRS-22 quality of life measures with SF-36: application in idiopathic scoliosis.
Comparison of a generic- with a disorder-specific health-related quality of life (HRQL) questionnaire. ⋯ SRS-22 Mental Health and Pain domain scores can be accurately calculated from correlating SF-36 domain scores. SRS-22 Function scores can be fairly well predicted from correlated SF-36 domain scores. Self-Image and Management Satisfaction/Dissatisfaction domain scores cannot be approximated from SF-36 domain scores.