Spine
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Randomized Controlled Trial
Preliminary evaluation of a computer-assisted tool for the design and adjustment of braces in idiopathic scoliosis: a prospective and randomized study.
Prospective and randomized clinical study. ⋯ It is possible to improve the design and adjustment of braces in AIS and to achieve 3-dimensional correction of scoliotic curves with the use of a computer-assisted tool allowing 3-dimensional visualization of the spinal curves and the external shape of the trunk.
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A questionnaire-based identification of adolescent idiopathic scoliosis (AIS) patients in a twin cohort. ⋯ We have found evidence for a genetic etiology in AIS, but the risk of developing scoliosis in 1 twin whose other twin has scoliosis is smaller than believed up until now.
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Clinical Trial
Intraoperative monitoring of motor-evoked potentials in children undergoing spinal surgery.
Clinical case series. ⋯ Combining spatial facilitation with a TES protocol improved monitoring of corticospinal motor pathways during spinal surgery in children. A ketamine-based anesthetic technique was preferred in children <6 years of age.
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The axonal growth potential of dorsal root ganglion (DRG) neurons in an organ culture system was investigated. ⋯ The results suggest that the cultured DRG neurons exhibit pathologic changes similar to those found in injured neurons. NGF-sensitive neurons, which include disc-innervating neurons, may have a greater potential to extend their axons in response to neuronal injury under pathologic conditions in the presence of TNF-alpha than GDNF-sensitive neurons.