Spine
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Randomized Controlled Trial Comparative Study
Epidural administration of spinal nerves with the tumor necrosis factor-alpha inhibitor, etanercept, compared with dexamethasone for treatment of sciatica in patients with lumbar spinal stenosis: a prospective randomized study.
Prospective randomized trial. ⋯ Our results indicate that epidural administration of a TNF-α inhibitor onto the spinal nerve produced pain relief, but no adverse event. TNF-α inhibitors may be useful tools for the treatment of radicular pain caused by spinal stenosis.
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Evaluation of the psychometric properties of a translated and culturally adapted questionnaire. ⋯ The FABQ outcome measure was successfully translated into Italian and proved to have a good factorial structure and psychometric properties that replicated the results of other existing versions. Its use is recommended for research purposes.
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Comparative Study
Major complications in revision adult deformity surgery: risk factors and clinical outcomes with 2- to 7-year follow-up.
Retrospective cohort comparative study. ⋯ Overall, 34.4% of patients experienced major complications after long revision fusion surgery. Different risk factors were identified for perioperative versus follow-up complications. The occurrence of a follow-up, not but perioperative, major complication seemed to have a negative impact on ultimate clinical outcome.
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Retrospective case series. ⋯ Osteogenic sarcoma of the mobile spine presents a significant challenge, and most patients die from their disease in spite of aggressive surgery and chemotherapy. Metastastic disease is associated with a worse prognosis. There is a trend toward improved survival with en bloc resection when compared with intralesional resection. Osteogenic sarcoma of the mobile spine is rare and historically has a very poor prognosis. We reviewed our cases of osteogenic sarcoma of the mobile spine to assess whether modern en bloc resection improved survival. Survival remains poor, but there is a trend toward improved survival with en bloc resection.
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A cross-sectional study of nonconsecutive cases (level III evidence). ⋯ Independent of the screw position, average t-EMG thresholds were always higher at the CV in the apex and above the apex regions, presuming that the distance from the pedicle to the spinal cord plays an important role in electrical transmission. The t-EMG technique has low sensitivity to predict screw malpositioning and cannot discriminate between medial cortex breakages and complete invasion of the spinal canal.