Spine
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Retrospective case series. ⋯ 4.
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Cross-sectional study of preselected cohort of patients with neck pain. ⋯ 2.
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Randomized Controlled Trial Multicenter Study
Randomized, double-blind, placebo-controlled, trial of transforaminal epidural etanercept for the treatment of symptomatic lumbar disc herniation.
Multicenter, randomized, double-blind, placebo-controlled trial. ⋯ Two transforaminal injections of etanercept provided clinically significant reductions in mean daily WLP and worst back pain compared with placebo for subjects with symptomatic LDH. Epidural etanercept may offer patients with sciatica a safe and effective nonoperative treatment.
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Reliability and agreement study, retrospective case series. ⋯ The AOSpine TL injury classification system is clinically relevant according to the consensus agreement of our international team of spine trauma experts. Final evaluation data showed reasonable reliability and accuracy, but further clinical validation of the proposed system requires prospective observational data collection documenting use of the classification system, therapeutic decision making, and clinical follow-up evaluation by a large number of surgeons from different countries.
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Multicenter Study
Deep wound infections after spinal fusion in children with cerebral palsy: a prospective cohort study.
Prospective cohort. ⋯ Deep wound infection occurred in 6.4% of children with CP after spinal fusion. The presence of a gastrostomy/gastrojejunostomy tube was a significant predictor of infection. Gram-negative organisms were the most common causative agents. Surgeons should be cognizant of these factors when treating children with CP and may consider Gram-negative antibiotic prophylaxis.