Spine
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Laboratory based controlled in vivo study. ⋯ These data demonstrate that the net effect on matrix in an animal model in vivo, as measured by gene expression, magnetic resonance imaging, histology, and total proteoglycan is antianabolic. This raises concern about this commonly used supplement, and future research is needed to establish the clinical relevance of these findings.
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Multicenter Study Clinical Trial
Impact of initial conservative treatment interventions on the outcomes of patients with osteoporotic vertebral fractures.
Prospective multicenter study. ⋯ 2.
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Validation and reliability analysis of the new SRS-Schwab classification for adult spinal deformity.
An inter- and intra-observer reliability study. ⋯ With the nonpremarked cases, this new SRS-Schwab system for patients with ASD could achieve good to excellent intra- and inter-observer reliability, but the definition of thoracic or lumbar curves was still predisposed to confusion. Overall, the SRS-Schwab system is a simple and clear classification system with incorporated spinopelvic parameters, which significantly increase its value for practical usage.