Spine
-
Comparative Study
Comparison of CatWalk analysis and von Frey testing for pain assessment in a rat model of nerve crush plus inflammation.
Assessment of pain-related behavior and immunohistology of the dorsal root ganglion in a rat model. ⋯ Our results demonstrate that the CatWalk system is useful for the measurement of pain-related behavioral change in our rat model in which nociception was indicated at a cellular level. Although further studies are needed, we think that this system is a valid alternative method for the evaluation of models of lumbar disease in rodents.
-
A prospective, randomized experimental research. ⋯ Minocycline is neuroprotective and contributes to functional improvement after traumatic SCI by eliminating the destructive process of secondary injury. Having both satisfying anti-inflammatory and antiapoptotic effects in experimental models, it promises to be of therapeutic use in human SCI.
-
Retrospective database analysis. ⋯ 3.
-
Retrospective database analysis. ⋯ Our study found that "off-label" use of BMP as an adjunct to cervical fusions was associated with increased rates of dysphagia in ACFs and increased costs for all cervical fusions. Our study does not measure long-term outcomes after discharge; however, the impact of increased inhospital costs, length of stay, and incidence of dysphagia with utilization of BMP should be considered prior to its use in cervical fusions.