Spine
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Numerous health care resources are utilized to treat low back pain (LBP) resulting from degenerative disc disease (DDD). Most patients with disc degeneration remain asymptomatic, and the degree of disc degeneration does not correlate with pain severity, making diagnosis and effective treatment challenging.
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Improving spinal fusion by optimizing scaffold and surface engineering is a topic of interest for both surgeons and researchers. Concerns regarding patient safety with off-label use of bone morphogenetic protein (BMP) have increased, and patients are choosing minimally invasive spine surgery to lessen morbidity by avoiding harvest of bone graft. These trends may be driving studies on how surgeons can avoid issues associated with biologics (e.g., cost, morbidity), while achieving efficacious and safe bone fusion.
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Randomized Controlled Trial Multicenter Study
Two-year Comparative Outcomes of MIS Lateral and MIS Transforaminal Interbody Fusion in the Treatment of Degenerative Spondylolisthesis. Part I: Clinical Findings.
A prospective, multicenter, institutional review board (IRB) approved study with randomized and observational study arms. ⋯ 2.
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Randomized Controlled Trial Multicenter Study
Two-Year Comparative Outcomes of MIS Lateral and MIS Transforaminal Interbody Fusion in the Treatment of Degenerative Spondylolisthesis. Part II: Radiographic Findings.
Prospective, multicenter, institutional review board approved study with randomized and observational study arms. ⋯ 2.
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Randomized Controlled Trial
Can Dysphagia Following Anterior Cervical Fusions With rhBMP-2 Be Reduced With Local Depomedrol Application?: A Prospective, Randomized, Placebo-Controlled, Double-Blind Trial.
A prospective, randomized, placebo-controlled, double-blind trial. ⋯ 1.