Spine
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Multicenter Study
Intrawound Vancomycin Powder Reduces Delayed Deep Surgical Site Infections Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis.
Retrospective. ⋯ 4.
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Multicenter Study
Prospective Registration Study for Establishing Minimal Clinically Important Differences in Patients Undergoing Surgery for Spinal Metastases.
Multicenter, prospective registry study. ⋯ II.
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A retrospective analysis. ⋯ 4.
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Prospective cohort using routinely collected health data. ⋯ Level III.
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Retrospective cohort. ⋯ Prophylactic antibiosis with IV vancomycin leads to a 2.5 times higher risk of infection compared with IV cefazolin in primary spine surgery. We recommend the routine use of IV cefazolin for infection prophylaxis, and caution against the elective use of alternative regimens like IV vancomycin unless clinically warranted.