Spine
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of three manual coccydynia treatments: a pilot study.
A prospective pilot study with independent assessment and a 2-year follow-up period was conducted. ⋯ There is a need for a placebo-controlled study to establish conclusively whether manual treatments are effective. This placebo must be an external treatment. A sample size of 190 patients would be required for 80% confidence in detecting a difference.
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Randomized Controlled Trial Clinical Trial
Should we give detailed advice and information booklets to patients with back pain? A randomized controlled factorial trial of a self-management booklet and doctor advice to take exercise for back pain.
Randomized controlled factorial trial. ⋯ Doctors can increase satisfaction and moderately improve functional outcomes in the period immediately after the consultation when back pain is worst, by using very simple interventions: either by endorsing a self-management booklet or by giving advice to take exercise. Previous studies suggest that simple advice and the same written information provide reinforcement. This study supports evidence that it may not be helpful to provide a detailed information booklet and advice together, where the amounts or formats of information differ.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
A multicenter, prospective, randomized trial evaluating a new hemostatic agent for spinal surgery.
A prospective, randomized trial comparing Proceed, a gelatin-based hemostatic sealant (treatment), with Gelfoam-thrombin (control) in stopping intraoperative bleeding during spinal surgery. ⋯ A significantly larger number of bleeding sites had achieved hemostasis with Proceed than with Gelfoam-thrombin at 1, 2, and 3 minutes after application. Proceed was as safe as Gelfoam-thrombin when used for hemostasis during spinal surgery procedures.
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Randomized Controlled Trial Clinical Trial
Lessons from a trial of acupuncture and massage for low back pain: patient expectations and treatment effects.
A subanalysis of data derived from a randomized clinical trial was performed. ⋯ The results of this study suggest that patient expectations may influence clinical outcome independently of the treatment itself. In contrast, general optimism about treatment, divorced from a specific treatment, is not strongly associated with outcome. These results may have important implications for clinical trial design and recruitment, and may help to explain the apparent success of some conventional and alternative therapies in trials that do not control for patient expectations. The findings also may be important for therapy choices made in the clinical setting.
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Randomized Controlled Trial Clinical Trial
Radiofrequency facet joint denervation in the treatment of low back pain: a placebo-controlled clinical trial to assess efficacy.
A prospective double-blind randomized controlled trial was performed. ⋯ Although radiofrequency facet joint denervation may provide some short-term improvement in functional disability among patients with chronic low back pain, the efficacy of this treatment has not been established.