Spine
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Randomized Controlled Trial Clinical Trial
The efficacy of antifibrinolytics in the reduction of blood loss during complex adult reconstructive spine surgery.
Controlled study to assess the efficacy of aprotinin and Amicar in reducing blood loss during complex spinal fusions. ⋯ For complex spinal operations with large blood losses, the half-dose aprotinin regimen will reduce blood loss and the need for blood components and may have a role in reducing postoperative lung injury.
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Randomized Controlled Trial Comparative Study Clinical Trial
Nonoperative treatment versus posterior fixation for thoracolumbar junction burst fractures without neurologic deficit.
A prospective clinical trial was conducted. ⋯ Short-segment posterior fixation provides partial kyphosis correction and earlier pain relief, but the functional outcome at 2 years is similar. Early activity to the point of pain tolerance can be safely allowed.
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Randomized Controlled Trial Clinical Trial
Periradicular infiltration for sciatica: a randomized controlled trial.
A randomized, double-blind trial was conducted. ⋯ Improvement during the follow-up period was found in both the methylprednisolone and saline groups. The combination of methylprednisolone and bupivacaine seems to have a short-term effect, but at 3 and 6 months, the steroid group seems to experience a "rebound" phenomenon.
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Randomized Controlled Trial Comparative Study Clinical Trial
Active therapy for chronic low back pain part 1. Effects on back muscle activation, fatigability, and strength.
Randomized prospective study of the effects of three types of active therapy on back muscle function in chronic low back pain patients. ⋯ Significant changes in muscle performance were observed in all three active therapy groups post-therapy, which appeared to be mainly due to changes in neural activation of the lumbar muscles and psychological changes concerning, for example, motivation or pain tolerance.
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Randomized Controlled Trial Clinical Trial
Active therapy for chronic low back pain: part 2. Effects on paraspinal muscle cross-sectional area, fiber type size, and distribution.
Randomized prospective study to compare the effects of three types of active therapy on the back muscle structure of chronic low back pain patients. ⋯ Three months active therapy is not sufficient to reverse the typical "glycolytic" profile of the muscles of cLBP patients or to effect major changes in backmuscle size. The alterations in muscle performance observed (increased strength and endurance; Part 1) werenot explainable on the basis of structural changes within the muscle.