Spine
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Observational Study
Perinatal Disorders and Small Birthweight are Significantly Associated With Small Vertebral Neural Canal Size in a Contemporary Pediatric Autopsy Sample.
A retrospective, nonblinded, single-center observational study. ⋯ Level 2.
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Double-blinded, prospective laboratory animal study. ⋯ These results demonstrate that spine surgery for unilateral laminectomy induces central sensitization that results in postoperative pain hypersensitivity. Intraoperative SCS after laminectomy may be able to mitigate the development of this hypersensitivity in appropriately selected cases.
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Retrospective cohort study. ⋯ 3.
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Prospective cohort study. ⋯ Less aggressive decompression performed similarly to wider decompression across multiple different patient-reported outcome measures at two years following surgery.
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Meta Analysis
Single Nucleotide Polymorphisms and Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis of the Literature.
Meta-analysis. ⋯ There seem to be associations between AIS and genetic SNP. Further larger studies should be conducted to validate the results.