Spine
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The mechanisms of apoptosis underlying a characteristic tissue reaction at the surface of the dorsal root ganglion (DRG) exposed to nucleus pulposus were studied in rats with special reference to the role of tumor necrosis factor-alpha (TNF). ⋯ TNF seemed to play a key role in induction of apoptosis of DRG cells, which resembled that induced by application of nucleus pulposus.
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Comparative Study
A comparison of the lenke and king classification systems in the surgical treatment of idiopathic thoracic scoliosis.
Retrospective case control study. ⋯ At intermediate follow-up, there does not seem to be significant radiographic or patient reported differences whether fusion levels are in agreement, longer, or shorter than those recommended by the Lenke or King classification systems.
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Investigation of the effect of static compression and anisotropy on the apparent diffusivity of glucose in bovine annulus fibrosus (AF). OBJECTIVE. To determine the apparent glucose diffusivity in 2 directions (axial and radial) of bovine AF under 3 levels of compressive strain (0%, 10%, and 20%). ⋯ Diffusion of glucose in bovine AF is dependent on strain and the direction of diffusion.
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Review Comparative Study
Clinical decision rules for identification of low back pain patients with neurologic involvement in primary care.
Descriptive study. ⋯ This study has identified differences between the guidelines in the clinical decision rules for identification of neurologic involvement including omission of categories. Decision-making that employs all 3 categories of neurologic involvement will arguably facilitate accurate and timely identification of patients with low back pain so affected in primary care.
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Review
Psychosocial interventions for low back pain in primary care: lessons learned from recent trials.
Workshop discussion and literature overview. ⋯ Despite the publication of recent "negative" results of psychosocial interventions for back pain, workshop participants remained optimistic about the importance of this line of research. Suggestions are given for a refocused research agenda on the effectiveness of psychosocial interventions for back pain in primary care.