Spine
-
Comparative Study
A relook into the association of the estrogen receptor [alpha] gene (PvuII, XbaI) and adolescent idiopathic scoliosis: a study of 540 Chinese cases.
A genetic association study of estrogen receptor-[alpha] gene (ESR1) with adolescent idiopathic scoliosis (AIS) in Chinese. ⋯ The previously reported association with curve severity could not be replicated in our large series of Chinese AIS patients. The current study also did not show any association of the 2 SNPs with increased risk of having AIS.
-
Comparative Study
Anterior exposure of the spine for removal of lumbar interbody devices and implants.
A retrospective review of a consecutive series of 14 patients operated on between March 1998 and April 2005. ⋯ Anterior removal of lumbar interbody devices placed anteriorly or posteriorly has a high incidence of complication. Average blood loss and hospital stay are increased with revision anterior surgery. The vascular complication rate is 2-fold higher at L4-L5 level compared to L5-S1.
-
Randomized Controlled Trial Multicenter Study Comparative Study
Effect of high-dose intravenous dexamethasone on postlumbar discectomy pain.
A prospective, randomized triple-blind clinical trial. ⋯ Intraoperative IV injection of 40 mg dexamethasone could effectively reduce postoperative radicular leg pain and narcotics usage in patients with single-level herniated lumbar disc.
-
Randomized Controlled Trial Comparative Study
Effectiveness of microdiscectomy for lumbar disc herniation: a randomized controlled trial with 2 years of follow-up.
Prospective randomized controlled trial. ⋯ Lumbar microdiscectomy offered only modest short-term benefits in patients with sciatica due to disc extrusion or sequester. Spinal level of the herniation may be an important factor modifying effectiveness of surgery, but this hypothesis needs verification.
-
Randomized Controlled Trial Comparative Study
Optimal end-tidal concentration of sevoflurane to test an ankle clonus in children.
A prospective randomized study on the end-tidal concentrations of sevoflurane at which ankle clonus existed. ⋯ The ankle clonus should be tested at 0.45% volume of end-tidal sevoflurane concentration in children undergoing scoliosis surgery during emergence from the general anesthesia.