Spine
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Comparative Study
Anatomic considerations of anterior transarticular screw fixation for atlantoaxial instability.
Anatomic parameters of C1 and C2 were measured in 30 dried human cervical spines. Anterior transarticular C1-C2 screws were placed in 15 cadaveric spines. ⋯ An anterior transarticular atlantoaxial screw 15-25 mm long can be inserted with a lateral angulation of 5-25 degrees relative to the sagittal plane and a posterior angulation of 10-25 degrees relative to the coronal plane. Additionally, in C1-C2 anterior plate fixation screws 15 mm long could be anchored in the inferior facet of the C1, and screws 9-15 mm long could be anchored in the C2 vertebral body.
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Comparative Study
Predictive signs of discogenic lumbar pain on magnetic resonance imaging with discography correlation.
The correlation between discogenic lumbar pain and disc morphology was investigated by using magnetic resonance imaging and discography. ⋯ Although the lumbar intervertebral discs with posterior combined anular tears are likely to produce pain, the validity of these signs for predicting discogenic lumbar pain is limited.
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Comparative Study
A human cadaver model for determination of pathologic fracture threshold resulting from tumorous destruction of the vertebral body.
Thoracic vertebrae were subjected to compressive loads after drilling of the centrum to simulate destruction from metastatic tumorous involvement. ⋯ The vertebral strength index can be used to predict the strength of any thoracic vertebra. When compared with an idealized vertebral strength index based on the intact vertebral cross-sectional area and normal bone mineral density, a patient's actual vertebral strength index can be used as one of the criteria for prophylactic stabilization.
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Comparative Study
The role of steroids and their effects on phospholipase A2. An animal model of radiculopathy.
The possible role of phospholipase A2 in an animal model for lumbar radiculopathy and mechanisms of epidural steroid injections were studied. ⋯ These results suggest that the behavioral pattern changes observed in the irritated nerve root model are caused in part by a high level of phospholipase A2 activity initiated by inflammation, and that the mechanism of action of epidural steroid injection in this model is inhibition of phospholipase A2 activity.
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Multicenter Study Clinical Trial Controlled Clinical Trial
Tuberculous lesions of the lumbosacral region. A 15-year follow-up of patients treated by ambulant chemotherapy.
A 15-year clinical follow-up of tuberculous lesions of the lumbosacral region. ⋯ In tuberculosis of the lumbosacral region, the development of kyphosis is minimal in patients older than 17 years, when growth has already stopped, and deformity is expressed more as foreshortening of the trunk. Children younger than 10 years old have more severe involvement with increased tendency toward greater kyphosis. They are also prone to progressive deformity through the years when the anterior growth plates are destroyed. Surgery is indicated in this group to prevent greater deformity.