Spine
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Randomized Controlled Trial Multicenter Study
Efficacy and safety of duloxetine in patients with chronic low back pain.
This was a randomized, double-blind, placebo-controlled clinical trial. ⋯ Duloxetine significantly reduced pain and improved functioning in patients with CLBP. The safety and tolerability were similar to those reported in earlier studies.
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Randomized Controlled Trial Comparative Study
Lumbar microdiscectomy with spinal anesthesia: comparison of prone and knee-chest positions in means of hemodynamic and respiratory function.
Prospective clinical study to compare the physiologic changes in lumbar disc surgery regarding to positions. ⋯ In conclusion, spinal anesthesia is appropriate for lumbar disc surgery with respect to the hemodynamic parameters in both prone and knee-chest positions, however, in terms of pulmonary functions, the knee-chest position can cause a restrictive effect. Therefore this position should be used cautiously in higher-risk patients.
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Randomized Controlled Trial Comparative Study
Is a behavioral graded activity program more effective than manual therapy in patients with subacute neck pain? Results of a randomized clinical trial.
A randomized clinical trial. ⋯ Based on this trial it can be concluded that there are only marginal, but not clinically relevant, differences between a BGA program and MT.
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Randomized Controlled Trial Multicenter Study
Analysis of segmental cervical spine vertebral motion after prodisc-C cervical disc replacement.
Retrospective study of patients enrolled in a prospective randomized Food and Drug Administration trial with single level cervical disc replacement (CDR) with the ProDisc-C (Synthes, Paoli, PA). ⋯ CDR approximates the different segmental sagittal and lateral ROM. Although C4/C5 had negative delta ROM in the sagittal and lateral planes, it provided a satisfactory final ROM. Long-term clinical outcome studies are needed to properly evaluate if these differences could ultimately affect the patients everyday life.
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Randomized Controlled Trial
The effectiveness of a posted information package on the beliefs and behavior of musculoskeletal practitioners: the UK Chiropractors, Osteopaths, and Musculoskeletal Physiotherapists Low Back Pain ManagemENT (COMPLeMENT) randomized trial.
Randomized controlled trial. ⋯ Printed educational material can shift LBP-related beliefs and reported behaviors of musculoskeletal practitioners, toward practice that is more in line with guideline recommendations.