Spine
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Randomized Controlled Trial
ISSLS prize winner: cost-effectiveness of two forms of circumferential lumbar fusion: a prospective randomized controlled trial.
Economic evaluation alongside a prospective, randomized controlled trial from a secondary care National Health Service (NHS) perspective. ⋯ From an NHS perspective, the trial data show that TC is not cost-effective in circumferential lumbar fusion. The use of FRA was both cheaper and generated greater QALY gains. In addition, FRA patients reported a greater return to work rate.
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Randomized Controlled Trial
Circumferential fusion is dominant over posterolateral fusion in a long-term perspective: cost-utility evaluation of a randomized controlled trial in severe, chronic low back pain.
Cost-utility evaluation of a randomized, controlled trial with a 4- to 8-year follow-up. ⋯ Circumferential fusion is dominant over instrumented posterolateral fusion, that is, both being significantly cheaper and significantly better in a long-term, societal perspective.
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Randomized Controlled Trial Multicenter Study Comparative Study
Qigong and exercise therapy in patients with long-term neck pain: a prospective randomized trial.
A randomized, controlled, multicenter trial: 1-year follow-up. ⋯ These results indicate that treatments including supervised qigong or exercise therapy resulting in reduced pain and disability can be recommended for persons with long-term nonspecific neck pain.
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Randomized Controlled Trial
Effect of low-dose ketamine on voltage requirement for transcranial electrical motor evoked potentials in children.
Randomized controlled trial. OBJECTIVE.: To determine the effect of low-dose ketamine on the voltage needed to elicit maximal amplitude of the motor-evoked response to transcranial electrical stimulation during propofol/remifentanil anesthesia in children undergoing scoliosis surgery. ⋯ Addition of low-dose ketamine to propofol/remifentanil anesthesia does not significantly reduce the voltage needed to elicit maximum amplitude of the motor-evoked response to transcranial electrical stimulation.
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Randomized Controlled Trial Multicenter Study Comparative Study
Recombinant activated factor VII in spinal surgery: a multicenter, randomized, double-blind, placebo-controlled, dose-escalation trial.
Randomized, placebo-controlled, double-blind, multicenter, Phase IIa study. ⋯ No safety concerns were indicated for the use of rFVIIa in patients at all doses tested; rFVIIa reduced adjusted blood loss and adjusted transfusions during spinal surgery.