Intensive care medicine
-
Intensive care medicine · Jan 1994
Randomized Controlled Trial Clinical TrialRapid fall in blood myoglobin in massive rhabdomyolysis and acute renal failure.
Myoglobin kinetics of removal from the circulation were studied in patients following massive rhabdomyolysis, to see if myoglobin remains for long in the circulation in the anuric state and if myoglobin elimination was affected by therapeutic manipulation such as haemofiltration or haemodialysis. ⋯ In patients with massive myoglobinaemia, the blood myoglobin rapidly fell independent of renal function or any therapeutic manipulation. The results indicate that extrarenal factors played a major role in disposing circulating myoglobin in such patients.