Intensive care medicine
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Intensive care medicine · Feb 1999
Randomized Controlled Trial Comparative Study Clinical TrialContinuous thermodilution cardiac output: clinical validation against a reference technique of known accuracy.
To evaluate the accuracy and precision of continuous thermodilution (CCO) by using a validated bolus thermodilution (BCO) reference technique as criterion standard. ⋯ Decreased precision of CCO as compared to iced BCO may, in clinical settings, be outweighed by the advantages of automated and continuous monitoring. Under research conditions, however, iced BCO remains the method of choice.
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Intensive care medicine · Feb 1999
Randomized Controlled Trial Clinical TrialEffects of early enteral nutrition on intestinal permeability and the development of multiple organ failure after multiple injury.
To determine how immediate enteral nutrition (EN) affects gut permeability and the development of multiple organ failure (MOF) in multiply injured patients. ⋯ In contrast with normal volunteers, the patients started on EN later than 24 h after admission to the ICU demonstrated increased intestinal permeability on the second day after sustaining multiple injury. Also, they had a more severe form of MOF than the group placed on EN immediately upon admission. However, early EN had no influence on the length of ICU stay or the time of mechanical ventilation.