Intensive care medicine
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Intensive care medicine · May 2004
Randomized Controlled Trial Multicenter Study Clinical TrialNoninvasive continuous positive airway pressure in elderly cardiogenic pulmonary edema patients.
To compare the physiological effects and the clinical efficacy of continuous positive airway pressure (CPAP) vs standard medical treatment in elderly patients (> or =75 years) with acute hypoxemic respiratory failure related to cardiogenic pulmonary edema. ⋯ Noninvasive continuous positive airway pressure promotes early clinical improvement in elderly patients attending emergency departments for a severe pulmonary edema, but only reduces early 48-h mortality.
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Intensive care medicine · May 2004
Randomized Controlled Trial Clinical TrialValue of the clinical pulmonary infection score for the identification and management of ventilator-associated pneumonia.
To evaluate the potential ability of an algorithm based on the clinical pulmonary infection score (CPIS) to identify and treat patients with bacterial ventilator-associated pneumonia (VAP) compared to a strategy based on quantitative cultures of bronchoscopic specimens. ⋯ A strategy based on the CPIS to decide which patients with suspected VAP should receive prolonged administration of antibiotics would appear to over-prescribe these agents, as compared to a strategy based on bronchoscopy.
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Intensive care medicine · May 2004
Randomized Controlled Trial Multicenter Study Clinical TrialPrevention of intravascular catheter-related infection with newer chlorhexidine-silver sulfadiazine-coated catheters: a randomized controlled trial.
The indication of antiseptic-coated catheters remains debated. ⋯ In the context of a low baseline infection rate, ACC were associated with a significant reduction of catheter colonisation and a trend to reduction of infection episodes, but not of bloodstream infection.
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Intensive care medicine · May 2004
Randomized Controlled Trial Clinical TrialEffect of cerebral perfusion pressure augmentation with dopamine and norepinephrine on global and focal brain oxygenation after traumatic brain injury.
To compare the effects of a cerebral perfusion pressure (CPP) intervention achieved with dopamine and norepinephrine after severe head injury. ⋯ If CPP is to be raised to a level higher than 65-70 mmHg, then it is important to recognise that the response to the intervention may be unpredictable and that the vasoactive agent used may be of importance.