Intensive care medicine
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Intensive care medicine · Apr 2007
Randomized Controlled Trial Multicenter StudyEpidemiology of sepsis in Germany: results from a national prospective multicenter study.
To determine the prevalence and mortality of ICU patients with severe sepsis in Germany, with consideration of hospital size. ⋯ The expected number of newly diagnosed cases with severe sepsis in Germany amounts to 76-110 per 100,000 adult inhabitants. To allow better comparison between countries, future epidemiological studies should use standardized study methodologies with respect to sepsis definitions, hospital size, and daily and monthly variability.
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Intensive care medicine · Apr 2007
Randomized Controlled TrialGlutamine kinetics during intravenous glutamine supplementation in ICU patients on continuous renal replacement therapy.
To investigate glutamine kinetics during continuous renal replacement therapy (CRRT) in multiple organ failure (MOF) patients with and without exogenous intravenous glutamine supplementation. ⋯ The loss of glutamine into the ultrafiltrate during CRRT in MOF patients suggests a greater need for exogenous glutamine than in patients without renal failure. The leg efflux and the filtration losses of glutamine were not affected in response to intravenous glutamine supplementation.