Intensive care medicine
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Intensive care medicine · Sep 2007
Comparison of lung injury after normal or small volume optimized resuscitation in a model of hemorrhagic shock.
To compare lung injury induced by a hemorrhagic shock resuscitated with normal saline or with small volumes of a hypertonic/hyperoncotic solution. ⋯ When included in an optimized and goal directed resuscitation, the use of normal saline or a small volume of hypertonic/hyperoncotic solution does not result in a different early hemorrhage-induced lung injury.
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Intensive care medicine · Sep 2007
Multicenter StudyContinuous renal replacement therapy: a worldwide practice survey. The beginning and ending supportive therapy for the kidney (B.E.S.T. kidney) investigators.
Little information is available regarding current practice in continuous renal replacement therapy (CRRT) for the treatment of acute renal failure (ARF) and the possible clinical effect of practice variation. ⋯ This study supports the notion that, worldwide, CRRT practice is quite variable and not aligned with best evidence.
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Intensive care medicine · Sep 2007
De-escalation therapy rates are significantly higher by bronchoalveolar lavage than by tracheal aspirate.
To assess outcomes with de-escalation therapy in ventilator-associated pneumonia (VAP). ⋯ For patients with VAP who have had appropriate treatment and shown a favorable clinical response, mortality and duration of stay can be further improved by de-escalation therapy.