Intensive care medicine
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Intensive care medicine · Jun 2008
Randomized Controlled Trial Multicenter Study Comparative StudyInitial efficacy and tolerability of early enteral nutrition with immediate or gradual introduction in intubated patients.
To compare the initial (D7) calorie intake and tolerability of two early enteral nutrition protocols in which the optimal flow rate was introduced either immediately or gradually. ⋯ When residual gastric volume is measured regularly and prokinetic agents are used, enteral nutrition can be started early and be introduced at optimal dose regimen, thereby providing better calorie intake. Serious adverse events required early enteral nutrition withdrawal in only 15 patients, with no difference in frequency between the groups.