Intensive care medicine
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Intensive care medicine · Jan 2009
Randomized Controlled Trial Multicenter StudyIntensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care.
To investigate the effectiveness of an enhanced software Model Predictive Control (eMPC) algorithm for intravenous insulin infusion, targeted at tight glucose control in critically ill patients, over 72 h, in two intensive care units with different management protocols. ⋯ In this feasibility study the eMPC algorithm provided similar, effective and safe tight glucose control over 72 h in critically ill patients in two different ICUs. Further development is required to reduce glucose sampling interval while maintaining a low risk of hypoglycaemia.
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Intensive care medicine · Jan 2009
Multicenter StudyThe epidemiology of acute respiratory distress syndrome in pediatric intensive care units in China.
To assess the incidence of, predisposing factors for, and the rates and relative risks of mortality from acute respiratory distress syndrome (ARDS) in pediatric patients. ⋯ ARDS has a high mortality in these Chinese PICUs, especially in those with pneumonia and sepsis, and adequate management including lung protective ventilation strategy is required.