Intensive care medicine
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Intensive care medicine · Jan 2011
Postoperative red blood cell transfusion and morbid outcome in uncomplicated cardiac surgery patients.
To evaluate postoperative red blood cell (RBC) transfusion and its association with postoperative cardiac events and multiorgan morbidity in uncomplicated cardiac surgery patients. ⋯ The data suggest a potential association between postoperative RBC transfusion and increased morbidity for cardiac surgery patients with low to moderate mortality risk profiles, adequate hemoglobin levels, and low bleeding rates.
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Intensive care medicine · Jan 2011
Effects of different mechanical ventilation strategies on the mucociliary system.
To evaluate the effects of different mechanical ventilation (MV) strategies on the mucociliary system. ⋯ Different MV strategies induce not only distal lung alterations but also morphological and physiological tracheal alterations leading to mucociliary system dysfunction.
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Intensive care medicine · Jan 2011
Randomized Controlled Trial Comparative StudyImpact of albumin compared to saline on organ function and mortality of patients with severe sepsis.
To determine the effect of random assignment to fluid resuscitation with albumin or saline on organ function and mortality in patients with severe sepsis. ⋯ Administration of albumin compared to saline did not impair renal or other organ function and may have decreased the risk of death.
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Intensive care medicine · Jan 2011
Determinants of arterial and central venous blood pressure variation in ventilated critically ill children.
Ventilation-induced arterial pressure variation predicts volume responsiveness in adults. Several factors are known to influence the interpretability of these variations. We analysed ventilation-induced variations in critically ill children with reference to ventilatory and circulatory parameters. ⋯ This preliminary study identified P(insp) as a determinant of SPV, PPV and CVP variation in children. Further independent determinants of SPV and PPV were baseline CVP and ventricular performance, both of which must be considered when interpreting pressure variations.