Intensive care medicine
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Intensive care medicine · Jan 2014
Review Meta AnalysisStress ulcer prophylaxis versus placebo or no prophylaxis in critically ill patients : A systematic review of randomised clinical trials with meta-analysis and trial sequential analysis.
To assess the effects of stress ulcer prophylaxis (SUP) versus placebo or no prophylaxis on all-cause mortality, gastrointestinal (GI) bleeding and hospital-acquired pneumonia in adult critically ill patients in the intensive care unit (ICU). ⋯ This systematic review using meta-analysis and TSA demonstrated that both the quality and the quantity of evidence supporting the use of SUP in adult ICU patients is low. Consequently, large randomised clinical trials are warranted.
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Intensive care medicine · Jan 2014
Comparative StudyImproved clinical and economic outcomes in severe bronchiolitis with pre-emptive nCPAP ventilatory strategy.
Severe bronchiolitis is the leading cause of admission to the pediatric intensive care unit (PICU). Nasal continuous positive airway pressure (nCPAP) has become the primary respiratory support, replacing invasive mechanical ventilation (MV). Our objective was to evaluate the economic and clinical consequences following implementation of this respiratory strategy in our unit. ⋯ nCPAP in severe bronchiolitis is associated with a significant improvement in patient management as shown by the reduction in invasive care, LOV, PICU LOS, hospital LOS, and economic burden.
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Intensive care medicine · Jan 2014
Letter Case ReportsTissue necrosis after propofol extravasation.