Intensive care medicine
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Intensive care medicine · Feb 2014
Randomized Controlled Trial Multicenter StudyEarly postoperative prophylactic noninvasive ventilation after major lung resection in COPD patients: a randomized controlled trial.
To investigate whether prophylactic postoperative NIV prevents respiratory complications following lung resection surgery in COPD patients. ⋯ Prophylactic postoperative NIV did not reduce the rate of ARE in COPD patients undergoing lung resection surgery and did not influence other postoperative complications rates, mortality rates, and duration of ICU and hospital stay.
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Intensive care medicine · Feb 2014
Randomized Controlled Trial Multicenter Study Comparative StudyImpact of the humidification device on intubation rate during noninvasive ventilation with ICU ventilators: results of a multicenter randomized controlled trial.
The use of heat and moisture exchangers (HME) during noninvasive ventilation (NIV) can increase the work of breathing, decrease alveolar ventilation, and deliver less humidity in comparison with heated humidifiers (HH). We tested the hypothesis that the use of HH during NIV with ICU ventilators for patients with acute respiratory failure would decrease the rate of intubation (primary endpoint) as compared with HME. ⋯ In this study, the short-term physiological benefits of HH in comparison with HME during NIV with ICU ventilators were not observed, and no difference in intubation rate was found. The physiologic effects may have been obscured by leaks or other important factors in the clinical settings. This study does not support the recent recommendation favoring the use of HH during NIV with ICU ventilators.
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Intensive care medicine · Feb 2014
Randomized Controlled Trial Multicenter Study Comparative StudyTight computerized versus conventional glucose control in the ICU: a randomized controlled trial.
The blood glucose target range and optimal method to reach this range remain a matter of debate in the intensive care unit (ICU). A computer decision support system (CDSS) might improve the outcome of ICU patients through facilitation of a tighter blood glucose control. ⋯ Tight computerized glucose control with the CDSS did not significantly change 90-day mortality and was associated with more frequent severe hypoglycemia episodes in comparison with conventional glucose control.