Intensive care medicine
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Intensive care medicine · Jul 2014
Multicenter Study Observational StudyTigecycline use in critically ill patients: a multicentre prospective observational study in the intensive care setting.
This prospective observational study aimed at describing prescription patterns of tigecycline and patient outcomes in 26 French intensive care units (ICU). ⋯ Tigecycline success rates appear comparable to those reported in clinical studies in ICU with severe infections. Tigecycline could be an alternative in ICU patients.
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Intensive care medicine · Jul 2014
Randomized Controlled Trial Multicenter StudyLong-term outcomes in patients with severe sepsis randomised to resuscitation with hydroxyethyl starch 130/0.42 or Ringer's acetate.
We assessed long-term mortality and hospitalisation in patients with severe sepsis resuscitated with hydroxyethyl starch (HES) or Ringer's acetate. ⋯ The long-term mortality rates did not differ in patients with severe sepsis assigned to HES 130/0.42 versus Ringer's acetate, but we could not reject a 24% relative increased or a 4% relative decreased mortality at 1 year with HES at the 95% confidence level.
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Intensive care medicine · Jul 2014
Randomized Controlled Trial Multicenter StudyOffering the opportunity for family to be present during cardiopulmonary resuscitation: 1-year assessment.
To evaluate the psychological consequences among family members given the option to be present during the CPR of a relative, compared with those not routinely offered the option. ⋯ At 1 year after the event, psychological benefits persist for those family members offered the possibility to witness the CPR of a relative in cardiac arrest.
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Intensive care medicine · Jul 2014
Randomized Controlled Trial Multicenter StudyHelmet CPAP vs. oxygen therapy in severe hypoxemic respiratory failure due to pneumonia.
The efficacy of noninvasive continuous positive airway pressure (CPAP) to improve outcomes in severe hypoxemic acute respiratory failure (hARF) due to pneumonia has not been clearly established. The aim of this study was to compare CPAP vs. oxygen therapy to reduce the risk of meeting criteria for endotracheal intubation (ETI). ⋯ Helmet CPAP reduces the risk of meeting ETI criteria compared to oxygen therapy in patients with severe hARF due to pneumonia.