Intensive care medicine
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Intensive care medicine · Dec 2015
Editorial CommentChasing the elusive notion of delirium causality.
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Intensive care medicine · Dec 2015
Meta Analysis Comparative StudyCitrate versus heparin anticoagulation for continuous renal replacement therapy: an updated meta-analysis of RCTs.
The purpose of this study was to evaluate the effect and safety of citrate versus heparin anticoagulation for continuous renal replacement therapy (CRRT) in critically ill patients by performing a meta-analysis of updated evidence. ⋯ Given the lower risk of circuit loss, filter failure, bleeding, and HIT, regional citrate should be considered a better anticoagulation method than heparin for CRRT in critically ill patients without any contraindication.
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Intensive care medicine · Dec 2015
Multicenter StudyOrganizational characteristics, outcomes, and resource use in 78 Brazilian intensive care units: the ORCHESTRA study.
Detailed information on organization and process of care in intensive care units (ICU) in emerging countries is scarce. Here, we investigated the impact of organizational factors on the outcomes and resource use in a large sample of Brazilian ICUs. ⋯ In emerging countries such as Brazil, organizational factors, including the implementation of protocols, are potential targets to improve patient outcomes and resource use in ICUs.