Intensive care medicine
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Intensive care medicine · Feb 2015
Review Meta AnalysisEffects of levosimendan for low cardiac output syndrome in critically ill patients: systematic review with meta-analysis and trial sequential analysis.
To assess the benefits and harms of levosimendan for low cardiac output syndrome in critically ill patients. ⋯ The available evidence is inconclusive whether or not levosimendan may have a beneficial effect on mortality due to risks of systematic errors and random errors. Further well-designed randomised trials are needed.
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Intensive care medicine · Feb 2015
Applying mean systemic filling pressure to assess the response to fluid boluses in cardiac post-surgical patients.
To evaluate an analogue of mean systemic filling pressure (P(msa)) and derived variables to quantitatively assess the effectiveness of volume expansion in increasing cardiac output. ⋯ Using an algorithm to derive a mean systemic filling pressure analogue, cardiac power and dynamic measures of the venous return pressure gradient relative to the mean systemic filling pressure provided an assessment of the efficiency of volume expansion in post-surgical cardiac patients.