Intensive care medicine
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Intensive care medicine · Jun 2024
Multicenter StudyThe role of centre and country factors on process and outcome indicators in critically ill patients with hospital-acquired bloodstream infections.
The primary objective of this study was to evaluate the associations between centre/country-based factors and two important process and outcome indicators in patients with hospital-acquired bloodstream infections (HABSI). ⋯ Centre/country factors should be targeted for future interventions to improve management strategies and outcome of HABSI in ICU patients.
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Intensive care medicine · Jun 2024
Multicenter StudyFactors associated with successful liberation from continuous renal replacement therapy in children and young adults: analysis of the worldwide exploration of renal replacement outcomes collaborative in Kidney Disease Registry.
Continuous renal replacement therapy (CRRT) is used for supportive management of acute kidney injury (AKI) and disorders of fluid balance (FB). Little is known about the predictors of successful liberation in children and young adults. We aimed to identify the factors associated with successful CRRT liberation. ⋯ Inability to liberate from CRRT was common in this multinational retrospective study. Modifiable and non-modifiable factors were associated with successful liberation. These results may inform the design of future clinical trials to optimize likelihood of CRRT liberation success.