Journal of pediatric psychology
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To identify methodologic problems found in follow-up studies of infants at biologic and environmental risk and provide solutions and recommendations. ⋯ Main-effect models are not useful; confounding and mediating variables must be identified. In addition, the following are needed: alternative analytic techniques, more precise subject selection and characterization of risk factors, geographically defined samples, broadened scope of outcome measures, and use of epidemiologic techniques.