The American journal of medicine
-
Review Meta Analysis
Subglottic secretion drainage for preventing ventilator-associated pneumonia: a meta-analysis.
To assess the efficacy of subglottic secretion drainage in preventing ventilator-associated pneumonia. ⋯ Subglottic secretion drainage appears effective in preventing early-onset ventilator-associated pneumonia among patients expected to require >72 hours of mechanical ventilation.
-
Meta Analysis
Mortality in systemic sclerosis: an international meta-analysis of individual patient data.
Studies on mortality associated with systemic sclerosis have been limited by small sample sizes. We aimed to obtain large-scale evidence on survival outcomes and predictors for this disease. ⋯ Systemic sclerosis confers a high mortality risk, but there is considerable heterogeneity across settings. Internal organ involvement and anti-topoisomerase I antibodies are important determinants of mortality.