The American journal of medicine
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No leisure time physical activity (NO-LTPA) continues to be a leading behavioral driver of poor health outcomes in the United States. The current investigation explores the relationship between, short term, longitudinal changes in social vulnerability and NO-LTPA within the context of culturally distinct U.S. regions. ⋯ These current findings indicate the SVI-NO-LTPA crisis within a crisis continues to be a factor in the U.S. The fact that there was a statistical signal between SVI and NO-LTPA change indicates improving the former may likewise improve the latter.
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Renin-angiotensin system (RAS) inhibitors at higher target doses reduce the risk of death in patients with heart failure with reduced ejection fraction (HFrEF). Less is known about their effectiveness in octogenarians, the examination of which was the objective of this study. ⋯ These findings provide evidence that in octogenarians with HFrEF, the use of RAS inhibitors at higher target (vs below-target) doses is associated with lower risks of death and kidney failure.