Neurosurgery
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Review Meta Analysis Comparative Study
Racial differences in cerebral vasospasm: a systematic review of the literature.
Despite a significant body of clinical research and the widespread use of early intervention with aggressive postoperative management, cerebral vasospasm (CV) continues to contribute significantly to the morbidity and mortality of aneurysmal subarachnoid hemorrhage (aSAH). Many studies have evaluated predictive factors, although none to date has investigated a possible difference in the incidence of CV between Asian and white patients. We present a review of the modern aSAH literature to examine the incidence of CV in Japan and Europe, two highly researched populations. ⋯ Patients in Japanese studies were more likely to experience CV after aSAH across diagnostic methods. This may be a manifestation of genetic differences between Japanese and European populations. Clinicians should consider possible patient differences when interpreting CV research conducted in these populations.
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Review Meta Analysis Comparative Study
Racial differences in cerebral vasospasm: a systematic review of the literature.
Despite a significant body of clinical research and the widespread use of early intervention with aggressive postoperative management, cerebral vasospasm (CV) continues to contribute significantly to the morbidity and mortality of aneurysmal subarachnoid hemorrhage (aSAH). Many studies have evaluated predictive factors, although none to date has investigated a possible difference in the incidence of CV between Asian and white patients. We present a review of the modern aSAH literature to examine the incidence of CV in Japan and Europe, two highly researched populations. ⋯ Patients in Japanese studies were more likely to experience CV after aSAH across diagnostic methods. This may be a manifestation of genetic differences between Japanese and European populations. Clinicians should consider possible patient differences when interpreting CV research conducted in these populations.
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A major concern in surgery is the prevention or control of bleeding. The ligature and the clip are the hallmarks of the last century of modern surgery. Therapeutic embolization is not really used to stop hemorrhage but to treat aneurysms and so prevent future rupture and bleeding. ⋯ Unfortunately, there are few areas in the central nervous system where such pressure can be applied, although it is a considerable help in opening muscle layers where self-retaining retractors will be used. Low-pressure venous bleeding may be controlled by application of gelfoam, surgically, or a bit of crushed muscle supported temporarily by a wet cottonoid pledget without occlusion of the venous channel. Historically, hot actual cautery or boiling oil were used to achieve hemostasis by forming a large tissue coagulum, which usually prevented bleeding until the entire dead mass sloughed away.