Neurosurgery
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Review Meta Analysis
The role of radiosurgery to the tumor bed after resection of brain metastases.
Optimal postoperative management paradigm for brain metastases remains controversial. ⋯ Our systematic review supports the use of radiosurgery as a safe and effective strategy for adjuvant treatment of brain metastases, particularly when gross total resection has been achieved. With all limitations of comparisons between studies, no increase in local recurrence or decrease in overall survival compared with rates with adjuvant whole-brain radiation therapy was found.