Neurosurgery
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Review
Prognostic Factors in Patients With Spinal Chordoma: An Integrative Analysis of 682 Patients.
The low incidence of spinal chordoma precludes a prospective study of prognostic factors with a large patient cohort. ⋯ In patients with spinal chordoma, young age, location in sacral spine, dedifferentiated pathology, and chemotherapy were negative predictors of PFS, while young and old age, bladder or bowel dysfunction at presentation, dedifferentiated pathology, recurrence or progression, and metastases portended a worse OS.