Cancer chemotherapy and pharmacology
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Cancer Chemother. Pharmacol. · Nov 2008
Multicenter StudyUse of the folinic acid/5-fluorouracil/irinotecan (FOLFIRI 1) regimen in elderly patients as a first-line treatment for metastatic colorectal cancer: a Phase II study.
The aim of this study was to evaluate the effects of a combination of folinic acid, 5-fluorouracil (5FU) and irinotecan (FOLFIRI 1) administered every 2 weeks in a population of elderly subjects with advanced colorectal cancer. ⋯ The FOLFIRI 1 regimen is a valid therapeutic option for elderly patients in good clinical condition.