Irish journal of medical science
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Review Case Reports
Malignant phaeochromocytoma metastasising to the breast.
Nearly one-quarter of metastatic tumours in the breast are from an occult extramammary tumour, usually a lung carcinoma. ⋯ This is the first published case of a phaeochromocytoma metastasising to the breast, and demonstrates the challenge that extramammary tumours in the breast can pose for the pathologist.
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Schizophrenia is a common mental illness with an incidence of 15 new cases per 100,000 population per year. ⋯ There have been considerable advances in schizophrenia research over the past 20 years. Future study of Indices of neural development will help advance our understanding of this common, disabling mental illness.
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Multicenter Study
Primary care anticoagulant management using near patient testing.
Indications for anticoagulant treatment are increasing and new approaches to anticoagulant services require a shift from hospital to primary care. ⋯ This study confirmed the validity of anticoagulant management using the CoaguCheck monitor in primary care.
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In anticipation of vaccine development this study sought to determine the incidence, disease burden and associated financial burden of rotavirus (RV) infection, in hospitalised children. ⋯ CA RV infection accounted for 1% of all admissions during the study period at a minimum cost of Euro728.40 per case. A safe and effective vaccine could reduce morbidity and advantage children by allowing redeployment of healthcare resources to other critical areas.
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Methylprednisolone is the only neuroprotective therapy advocated in acute non-penetrating spinal cord injury. Trials indicate improved neurological outcome following early administration of a high dose regime. The National Spinal Injuries Unit (NSIU) has promoted this regime by a simple laminated poster sent to all Irish A&E departments. ⋯ There was poor documentation of prescription orders and timing of administration. Only six patients had clear documentation allowing confirmation of adherence to the protocol of the National Acute Spinal Cord Injury Study (NASCIS) III trial.