Irish journal of medical science
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Randomized Controlled Trial Comparative Study Clinical Trial
Controlled trial of maintenance treatment of intravenous buprenorphine dependence.
Buprenorphine dependence is a relatively novel addiction. ⋯ These results support the efficacy and safety of oral methadone and sublingual buprenorphine tablets for injection buprenorphine-dependent patients.
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Age-related macular degeneration (AMD) is the leading cause of visual impairment and blindness in the Western World in those aged 65 and older. At present, several treatment modalities are utilised and several more are undergoing investigation in an attempt to retard the occurrence and progression of this devastating condition. ⋯ While no curative treatment for this condition currently exists, early recognition and treatment, if indicated, have been shown to reduce the risk of severe vision loss in patients with this condition.
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Comparative Study
Risperidone compared with olanzapine in a naturalistic clinical study in Ireland: a cost analysis.
Risperidone and olanzapine are thought to have similar clinical effects. This study was designed to compare costs of treatment. ⋯ Risperidone was associated with significantly lower drug treatment costs.
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Target blood pressure control in patients with type 2 diabetes should be 130/85 mmHg or less; however, it is not clear how achievable this target is in clinical practice. ⋯ Adequate blood pressure control was underachieved in this patient group underlying the difficulty in treating blood pressure to target values in patients with type 2 diabetes in the setting of outpatient diabetes clinics. A more aggressive strategy, in particular the use of multiple antihypertensive agents should be adopted.
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[corrected] Urological complications are the major cause of ill health during childhood and adult life of patients with spina bifida but the significance of urinary tract disease on the individual and the healthcare services is underemphasised. ⋯ This study highlights the surgical commitment for units caring for patients with spina bifida, the important considerations for the future healthcare services, and the range and severity of urological diseases encountered by these patients.