Irish journal of medical science
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Children with cerebral palsy may be at greater risk of being overweight or obese than their typically developed peers due to a number of biomechanical, behavioural, or medical issues that restrict participation. It has been a concern of our multi-disciplinary team that a greater number of children with cerebral palsy were presenting as overweight or obese. However, there are conflicting results in the literature as to prevalence and trends of overweight and obesity in these children. ⋯ Prevalence of overweight and obesity is not increasing in Irish ambulatory children with cerebral palsy. However, a higher prevalence of overweight and obesity was evident when compared with their typically developed Irish peers. It is therefore important that prevalence and trends are monitored.
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In August 2019, 3848 children in Ireland were faced with emergency homelessness [1]. In recent years, lack of affordable housing, unemployment and shortage of rental properties have been the primary driving factors for the potentially devastating impact of familial homelessness in our society [1]. Our aim was to evaluate current knowledge on the psychological impact of homelessness in children. ⋯ Our study highlights violence, aggression and poor academic learning outcomes to be just some of the key findings in our review of homelessness in childhood, worldwide. Unfortunately, there has been minimum research to date on paediatric homelessness within the context of the Irish population. We anticipate this review to be the first chapter in a multipart series investigation to evaluate the psychological morbidity of paediatric homelessness within the Irish Society.
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There is limited information on reference values for lipids and lipoproteins in an Irish population. In this observational study, we have described the distributions of lipids in a large Irish cohort. ⋯ This study provides lipid reference values for clinical biochemistry laboratories and clinicians working in Ireland. It is informative for public health initiatives wishing to target dyslipidaemia as a modifiable risk for cardiovascular disease and for investigators researching geographical and temporal variances in lipid parameters.
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The incidence of thyroid cancer (TC) is increasing rapidly worldwide. The target therapy for papillary TC (PTC) is limited, and the studies of PTC prognostic biomarkers are not common. As a new member of annexin A (ANXA) family, the function and clinical significance of ANXA10 in PTC have not been well investigated. ⋯ ANXA10 expression was upregulated in PTC, and it was an independent prognostic biomarker of PTC, suggesting that ANXA10 may be a promising target for individual treatment of ANXA10.