Irish journal of medical science
-
There is no randomized controlled trial that demonstrated the efficacy of antiviral therapy against COVID-19 yet. However, physicians are prescribing different drugs to a large part of COVID-19 population in the hope they will cure them. This does not reflect the evidence-based medicine approach. What we need is more evidence-based knowledge about what routine care practices we should to apply to ameliorate symptoms of patients and fight COVID-19 pathology.
-
Although laparoscopic appendectomy (LA) is considered to be minimally invasive compared with open appendectomy (OA), there are few studies showing this in terms of cytokines and oxidative stress markers. ⋯ LA had a more positive effect on oxidative DNA damage, IL-1β and IL-37 than the OA. In addition, surgical stress was reduced with LA.
-
Modern oncological and operative outcomes in esophageal cancer: the St. James's hospital experience.
Oesophageal cancer has a reputation for poor survival, and a relatively high risk of major postoperative morbidity and mortality. Encouragingly, a recent international cancer registry study reports a doubling of survival outcomes in Ireland over the last 20 years. This study focused on both oncologic and operative outcomes in patients treated with curative intent requiring surgery at a high-volume center. ⋯ Consistent with registry data on population survival for oesophageal cancer, this study highlights markedly improved survival outcomes in patients treated curatively, reflecting international trends, as well as low mortality rates; however, cardiorespiratory complications remain significant.
-
This study aimed to determine the role of ONSD measurement by US for diagnosis of high ICP in TBI patients. ⋯ ONSD measurement by ultrasound is a good screening tool for high ICP in traumatic brain injury patients.
-
There are no many data on association between progression rate of Guillain-Barré syndrome (GBS) and disease outcome. ⋯ Faster progression of GBS does not imply a poorer short-term functional outcome of the disease.