Irish journal of medical science
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Cancer gene panel testing is available in Ireland. The need for a clear strategy to deal with patient information generated from tumour genomic testing is recognised as a challenge in the National Cancer Strategy. However, the public's attitude and opinions regarding these results is not known in Ireland. ⋯ This is the first prospective Irish study to assess opinions surrounding cancer gene results. Addressing patient's lack of information as regards genetic testing is the first step in establishing a national cancer genetics testing programme in Ireland.
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Review
A brief literature review of the psychological benefits of volunteerism in watersports inclusion.
The 2009 National Guidelines on Physical Activity for Ireland assert that 'all people with disabilities should be active'. Events such as the Watersports Inclusion Games invite individuals across the full spectrum of abilities to take part in physical activity in the form of adaptive watersports. This literature review aims to assess the value of inclusive watersport events such as this in the context of what is currently published on the motivation and benefits for volunteers in watersports inclusion. ⋯ The outcomes of this review suggest that, while there are many papers published on the benefits for volunteers in general and in sport, there is a relative paucity of literature on volunteers in inclusive sport, and even less relating to inclusive watersports. This review identifies a powerful opportunity to provide evidence to support the benefits of inclusive watersport for both participants and volunteers. Further research is required on why volunteers become involved in inclusive watersports and the benefits they derive from their involvement.
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Insulin resistance plays a major role in the pathogenesis of polycystic ovary syndrome (PCOS). Therefore, there is a growing interest in the use of insulin sensitizer drugs in the treatment of PCOS. Research in recent years has shown that sitagliptin has been reported to improve ovarian cycles and ovulation in PCOS patients. ⋯ We conclude that sitagliptin can improve the maturation of oocytes and embryos' quality more effectively than metformin, in PCOS patients undergoing ICSI.
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Crohn's disease (CD) primarily involves gastrointestinal tract; however, it can present with extraintestinal manifestations (EIMs), which leads to significant morbidity. Frequency of EIMs and associated risk factors vary due to genetic and environmental differences in studies. ⋯ Although the immunological and clinical associations between EIMs and CD cannot be fully elucidated, identifying specific relationships of immune-mediated diseases will help to better understand CD pathogenesis.
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Lisfranc injuries form a distinct group of rare but severe injury. Literature suggests a low incidence, but failure to diagnose these injuries early and its subsequent delay in management will affect the patient's mobility and quality of life significantly. The preferred mode of management is said to be surgical. Conversely, the method of intervention for patients not suitable for surgery is less clear. ⋯ We believe that definitive treatment in the form of surgical fixation and anatomical reduction has more influence on the functional outcome than the timing of the surgical fixation in case of subtle Lisfranc injuries.